You can do it with this code.
// Language to search.
$find = 'French';
// Getting all the available languages.
$languages = \Drupal::service('language_manager')->getStandardLanguageList();
$key = key(array_filter($languages, function ($array) use ($find) {
if (array_search($find, $array) === FALSE) {
return FALSE;
}
return TRUE;
}));
// If you have the devel module installed you can use the dpm function.
dpm($key);
Or, if you are on PHP 7.4+:
// Language to search.
$find = 'French';
$languages = \Drupal::service('language_manager')::getStandardLanguageList();
$langcode = key(array_filter($languages, fn ($lang) => in_array($find, $lang)));