Drupal Commerce refuses to flush the cache_form table when cron tasks run. I know it is most likely a known bug and it has tens of solutions. (I will probably just set cron task to flush it somewhere in the midnight every day.)
Does it speed up Drupal in any way?
It is part of a cache obviously, but I did not noticed any better performance whether the table size. More or less I experience slowdown, but it might be related to something else.